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-7-Fuji IX GP1254 Fluoride Release of Dental Restoratives When Brushed With Fluoridated ToothpastePoster Presentation3:45 PM–5:00 PM Mar 23, 2017 CC, West HallAuthors:Authors:Nancy Epstein (Presenter)Tufts University School of Dental MedicineTamar Roomian, Tufts University School of Dental MedicineRonald Perry, Tufts University School of Dental MedicineAbstract: Objectives: Fluoride is often added to dental materials because it is known to inhibit caries progression and increase enamel strength. The purpose of this study was to determine if the progression and increase enamel strength. The purpose of this study was to determine if the level of fluoride ions released from various dental restorative materials could be sustained when brushed with a fluoridated toothpaste.Methods: Eighty samples, 5mm by 2mm, were prepared from four different restorative materials (n=20): (Group 1) ACTIVA™BioACTIVERESTORATIVE™(Pulpdent); (Group 2) Fuji IX GP®(GC America); (Group 3) RelyX™LutingPlus Cement (3M ESPE); (Group 4) Filtek™Supreme Ultra Universal Restorative (3M ESPE). Ten samples from each group were brushed with 0.25g of Colgate Total®Clean Mint toothpaste containing 0.24% sodium fluoride for 2 minutes every day while the other ten samples from each group served as the control. A fluoride ion analyzer while the other ten samples from each group served as the control. A fluoride ion analyzer (Thermo Scientific Orion Star™A214) was pre-calibrated with 1, 2, and 10ppm buffer solutions prior to measurements and fluoride release was measured on days 1, 5, 10, 15, and 20. Data was analyzed using a three-way ANOVA model of log transformed data with a Tukey-Kramer post-hoc test and comparisons were considered to be significant at p<0.05.Results: The control groups that were not brushed with toothpaste generally displayed significant decreases in fluoride release throughout the study (Fig. 1). When brushed with toothpaste, Groups 1 and 4 significantly sustained fluoride release with Group 1 releasing more fluoride ions each day except for day 5. Group 2 had a significant decrease in fluoride release until days 15 to each day except for day 5. Group 2 had a significant decrease in fluoride release until days 15 to 20. Group 3 sustained fluoride release between adjacent measurement days but had significant decreases overall (Fig. 2).Conclusions: This study demonstrated that the bio-active restorative is able to sustain fluoride release over time when brushed with fluoridated toothpaste compared to other restorative materials.Image(s):Student PresenterDisclosure Statement:The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: None.I have read the IADR policy on licensing.Signed by Nancy EpsteinReprinted with permission from the Journal of Dental Research, J Dent Res 96 (Spec Iss A):-7-Signed by Nancy Epsteinabstract number 1254, https://iadr2017.zerista.com/event/member/332679, 2017