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-43-MI Paste Plus0689 Color Change of White-Spot Lesions Treated With Various RemineralizingAgentsPoster Presentation11:00 AM–12:15 PM Mar 23, 2017CC, First Floor Authors:Authors:BreannaBirk(Presenter)Midwestern UniversityJohn Mitchell, Midwestern UniversityM. Teresa Pulido, Midwestern UniversityLisa Do, Midwestern UniversityShaghayeghAssar, Midwestern UniversityAbstract: Abstract: Objectives: White Spot Lesions (WSL) are the initial demineralizedstage in caries development. Arresting WSL is the first step in caries control. We compared 4 commercial products intended to remineralizeteeth by assessing their ability to reduce the appearance of WSL.Methods: A total of 60 extracted, human, non-carious molars, with three 4x3mm windows were subject to pH-cycling until WSL were visible. Teeth were randomly allocated to four groups. All teeth had one lesion arrested by covering it with wax. The remaining two lesions continued cycling with one receiving treatment twice a day following manufacturer’s instructions. Treatment groups (n=15 teeth each) were Reminpro(VOCO GmbH, Cuxhaven, Germany), Treatment groups (n=15 teeth each) were Reminpro(VOCO GmbH, Cuxhaven, Germany), ClinproTooth Crème (3M, St. Paul, MN), MI Paste Plus (GC, Alsip, IL), and Crest Kid’s (P&G, Cincinnati, OH), as a fluoride-containing toothpaste control. We used a BYK-Garner 6807 Color-Guide 45/0 Spectrophotometer (Paul N. Gardner, Pompano Beach, FL) to generate L, a, and b values. The ∆E values were calculated for color difference between: 1) treated lesion color (TL) and natural tooth surface color (NTS); 2) untreated lesion color (UTL) and NTS; as well as 3) arrested lesion (AL) and NTS.Results: All lesions had ∆E values that were detectable with the human eye, when compared to Results: All lesions had ∆E values that were detectable with the human eye, when compared to natural tooth color. The AL functioned as a base-line to compare how well the treatment prevented the lesion from further color change. Treatment with MI Paste Plus reduced the difference in color by the greatest amount and resulted in the lowest change in color when used on an existing lesion undergoing demineralization. See Table 1.Conclusions: Reminproslightly reduced the color change between the NTS and the treated lesion, while MI Paste Plus prevented further change of the lesion color. ClinproTooth Crème and Kid’s Crest Toothpaste allowed greater change in color of the lesion than the UTL.Reprinted with permission from the Journal of Dental Research, J Dent Res 96 (Spec Iss A):-43-abstract number 0689, https://iadr2017.zerista.com/poster/member/76535, 2017